Microencapsulation of Coenzyme Q sub(10) in Poly(ethylene glycol) and Poly(lactic acid) with Supercritical Carbon Dioxide

• Published in: Industrial & engineering chemistry research Vol. 51; no. 17; pp. 5840 - 5846-5840-5846
• Main Authors: Vergara-Mendoza, Maria del Socorro, Ortiz-Estrada, Ciro-Humberto, Gonzalez-Martinez, Juana, Quezada-Gallo, Jesus-Alberto
• Format: Journal Article
• Language: English
• Published: 02.05.2012
• Subjects: Carbon dioxide; Coenzymes; Differential scanning calorimetry; Dissolution; Electronics; Encapsulating; Glycols; Process parameters

The rapid expansion of supercritical solutions (RESS) process was applied to produce polymeric microparticles loaded with coenzyme Q sub(10) (coQ sub(10)). Mixtures of poly(lactic acid) (PLA)/(coQ sub(10)) and poly(ethylene glycol) (PEG)/(coQ sub(10)) containing a cosolvent were dissolved in supercr...