Investigation of the electrocatalytic function of Fe sub( 3)O sub( 4) nanoparticles and the application as cefotaxime sodium sensor

By a simple drop coating method, Fe3O4 nanoparticles (FeNP) were modified on a glassy carbon electrode to fabricate an amperometric sensor for cefotaxime sodium (CS) detection. The microstructure and electrochemical behaviour of the sensor were investigated by scanning electron microscope and electr...

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Bibliographic Details
Published inMicro & nano letters Vol. 6; no. 4; p. 284
Main Authors Wang, Mingyan, Xu, Xingyou, Yang, Jun, Yang, Xujie, Tong, Zhiwei
Format Journal Article
LanguageEnglish
Published 01.04.2011
Subjects
Electrodes
Glassy carbon
Nanoparticles
Nanostructure
Reduction
Scanning electron microscopy
Sensors
Sodium
Voltammetry
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Summary:By a simple drop coating method, Fe3O4 nanoparticles (FeNP) were modified on a glassy carbon electrode to fabricate an amperometric sensor for cefotaxime sodium (CS) detection. The microstructure and electrochemical behaviour of the sensor were investigated by scanning electron microscope and electrochemical impedance spectrum. The electrocatalytic ability of the sensor to CS reduction reaction in Britton-Robinson (B-R) buffer solution (pH 5.2) was investigated by cyclic voltammetry and differential pulse voltammetry. The results suggested that the proposed sensor exhibited an excellent electrocatalytic activity towards the reduction of CS with a well-defined reduction peak and an obvious decrease of overpotential. The catalytic currents of CS were linearly dependent on the concentrations of CS in the range from 0.15 to 25 mu M, with the detection limit of 0.1 mu M. The sensor exhibited good stability and reproducibility, and it was successfully applied to determine the CS concentrations in CS injection samples.
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ISSN:1750-0443