Insomnia in HIV-infected Patients: Pathophysiologic Implications

The prevalence of insomnia in the HIV-seropositive population is estimated to be 29-97%, far greater than the 10% general population prevalence. We carried out a systematic review to assess whether the prevalence of insomnia is indeed higher in HIV-seropositive patients and to better understand the...

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Bibliographic Details
Published inAIDS reviews Vol. 16; no. 1; p. np
Main Authors Low, Yinghui, Goforth, Harold, Preud'homme, Xavier, Edinger, Jack, Krystal, Andrew
Format Journal Article
LanguageEnglish
Published 01.01.2014
Subjects
Human immunodeficiency virus
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Summary:The prevalence of insomnia in the HIV-seropositive population is estimated to be 29-97%, far greater than the 10% general population prevalence. We carried out a systematic review to assess whether the prevalence of insomnia is indeed higher in HIV-seropositive patients and to better understand the correlates of insomnia in order to attempt to explain the dramatically higher prevalence. Nineteen studies met our search criteria and were included in this review. The rate of sleep disturbance identified in HIV-infected patients (29-97%) should not be com pared against the approximately 10% prevalence of clinically significant insomnia in the general population, which would suggest that HIV infection is associated with an alarming increase in sleep problems. Instead, this rate is best compared with the rate of sleep disturbance in the general population, which is roughly 33%.
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ISSN:1139-6121
1698-6997