Fragments of the internal transcribed spacer 1 of the pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5' arrow right 3' exoribonuclease 1

The portion of the internal transcribed spacer 1 found on 20S pre-rRNA accumulates in Saccharomyces cerevisiae lacking 5' arrow right 3' exoribonuclease 1, showing that an endonucleolytic cleavage at the 3' terminus of 18S rRNA is involved in the 20S pre-rRNA to 18S mature rRNA conver...

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Bibliographic Details
Published inJournal of bacteriology Vol. 173; no. 21; pp. 7024 - 7028
Main Authors Stevens, A, Hsu, CL, Isham, K R, Larimer, F W
Format Journal Article
LanguageEnglish
Published 01.01.1991
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Summary:The portion of the internal transcribed spacer 1 found on 20S pre-rRNA accumulates in Saccharomyces cerevisiae lacking 5' arrow right 3' exoribonuclease 1, showing that an endonucleolytic cleavage at the 3' terminus of 18S rRNA is involved in the 20S pre-rRNA to 18S mature rRNA conversion. Smaller fragments of the spacer sequence are also found. The exoribonuclease may be involved as a cytoplasmic RNase in the hydrolysis of the spacer.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0021-9193