Cytologic changes in the nasal secretions during the late nasal response

One hundred sixty-four patients with allergic rhinitis (104 patients with positive late nasal responses (LNRs) and 60 patients with negative nasal responses to allergen challenge), correlating with history and skin tests, were randomly selected for this study. Nasal challenges were repeated and supp...

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 93; no. 6; pp. 1068 - 1079
Main Authors Pelikan, Z, Pelikan-Filipek, M
Format Journal Article
LanguageEnglish
Published 01.01.1989
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Summary:One hundred sixty-four patients with allergic rhinitis (104 patients with positive late nasal responses (LNRs) and 60 patients with negative nasal responses to allergen challenge), correlating with history and skin tests, were randomly selected for this study. Nasal challenges were repeated and supplemented by cytologic examination of the nasal secretions (NSs). The cytologic examination of NS was also performed during 164 control challenges with phosphate-buffered saline. The cytologic examination of NS, accompanying the nasal challenge with allergen, appears therefore to be a valuable supplementary diagnostic parameter for the LNR and a promising model for further immunologic and clinical studies of the LNR.
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ISSN:0091-6749