Quinolones and multiresistant Plasmodium falciparum

• Published in: The Lancet (North American edition) Vol. 2; no. 8605; p. 281
• Main Authors: Midgley, J M, Keter, D W, Phillipson, J D, Grant, S, Warhurst, D C
• Format: Journal Article
• Language: English
• Published: 01.01.1988
• Subjects: Plasmodium falciparum

The authors have tested ciprofloxacin, by the 48 h super(3)H-hypoxanthine incorporation technique agaists a Thai multiresistant line of the parasite. The inhibitory concentration (IC) of ciprofloxacin observed was 5.2 mu g/ml, similar to the 8 mu g/ml reported previously. This indicates that the 4-q...