Synthesis and X-ray crystal structure analysis of 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydr o -naphthalen-1(2H)-one: Sertraline key intermediate analog

The novel bioactive compound 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydr o -naphthalen-1(2H)-one was synthesised in three different methods, namely, conventional, MW irradiation with solvent and MW irradiation without solvent. The synthesised compound was characterised by spec...

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Published inJournal of chemical research Vol. 2006; no. 11; pp. 730 - 732
Main Authors Kavitha, Chandagirikoppal V, Mantelingu, Kempegowda, Sarala, Gangadaraiah, S, Naveen, Anandalwar, Sridhar M, Shashidhara, Kanchugarakoppal S Javaregowda
Format Journal Article
LanguageEnglish
Published 01.11.2006
Subjects
Crystal structure
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Summary:The novel bioactive compound 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydr o -naphthalen-1(2H)-one was synthesised in three different methods, namely, conventional, MW irradiation with solvent and MW irradiation without solvent. The synthesised compound was characterised by spectroscopic techniques and finally confirmed by X-ray crystal structure analysis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Feature-1
ISSN:1747-5198
2047-6507
DOI:10.3184/030823406779173271