Clinical Characteristics and Prognostic Analysis of 107 Cases of Nasal NK T-cell Lymphoma

• Published in: Zhongliu fangzhi yanjiu Vol. 40; no. 9; pp. 873 - 876
• Main Authors: Chen, D, Yang, Y, Chen, G, Wu, J, Xiao, J, Wu, H, He, H-M, Chen, Y, Lin, J, Zou, S
• Format: Journal Article
• Language: Chinese
• Published: 25.09.2013
• ISSN: 1000-8578
• DOI: 10.3971/j.issn.1000-8578.2013.09.013

Objective To retrospectively analyze the clinical characteristics and long-term treatment outcome of 107 cases of extranodal NK/T-cell lymphoma of nasal type (ENKTL) and investigate the prognostic factors. Methods One hundred and seven cases of patients with pathologically confirmed ENKTL who were admitted to Fujian Provincial Tumor Hospital from January 2002 to December 2010 were analyzed. Univariate analysis was firstly applied for each clinical and laboratory characteristic. The statistically significant factors were then included in multivariate analysis. Results In 107 patients, 74 were male and 33 were female (M: F = 2.2:1), with median age of 42 years (range, 9 to 83 years). The most common sites of involvement were nasal cavity (75 cases, 70%), followed hy Waldeyer's ring (24 cases, 22%) and others (8 cases). Twelve cases (11%) involved in cervical lymph nodes and only 2 patients had bone marrow metastasis. According to the Ann Arbor staging system. 82% patients were staged as I/II. 83% had internatio