Hypothyroidism in rats does not lower mitochondrial ADP/O and H super(+)/O ratios

The authors investigated reports that mitochondria isolated from hypothyroid rats have decreased ADP/O and H super(+)/O ratios. They suggest that the lowering of the apparent ADP/O ratio in mitochondria from hypothyroid rats at low concentrations of mitochondrial protein is an experimental artefact...

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Bibliographic Details
Published inBiochemical journal Vol. 250; no. 2; pp. 477 - 484
Main Authors Hafner, R P, Brand, MD
Format Journal Article
LanguageEnglish
Published 01.01.1988
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Summary:The authors investigated reports that mitochondria isolated from hypothyroid rats have decreased ADP/O and H super(+)/O ratios. They suggest that the lowering of the apparent ADP/O ratio in mitochondria from hypothyroid rats at low concentrations of mitochondrial protein is an experimental artefact resulting from the breakdown of ADP to AMP.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0264-6021