Integration and spike intitiation in neuronal terminals

Axoaxonal synapses impinge on the terminals of neurons and are thought to play a crucial role in the regulation of synaptic transmission. In the crayfish brain, the terminals of several identified interneurons exhibit both EPSPs and IPSPs in response to cephalic sensory stimulation. The terminal arb...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of neuroscience Vol. 6; no. 6; pp. 1726 - 1732
Main Authors Wang-Bennett, L T, Glantz, R M
Format Journal Article
LanguageEnglish
Published 01.01.1986
Subjects
Freshwater
Procambarus clarkii
Online AccessGet full text

Cover

More Information
Summary:Axoaxonal synapses impinge on the terminals of neurons and are thought to play a crucial role in the regulation of synaptic transmission. In the crayfish brain, the terminals of several identified interneurons exhibit both EPSPs and IPSPs in response to cephalic sensory stimulation. The terminal arbors extend into primary sensory neuropils near the terminals of primary afferent axons of the antennae and statocysts. The EPSPs arise monosynaptically from primary afferent stimulation and can elicit action potentials. Bidirectional conduction is routinely observed. Terminal IPSPs are transmitted via a polysynaptic pathway. Furthermore, two morphological classes of synaptic profiles impinge on the presynaptic terminals. These results indicate that the neuron terminal can function as a second, independent site of synaptic integration.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Feature-2
ISSN:0270-6474