Resolution of vitreomacular traction following intravitreal ranibizumab in cases of ocular toxoplasmosis with choroidal neovascularization

• Published in: Therapeutics and clinical risk management Vol. 9; pp. 391 - 394
• Main Authors: Petrou, Petros, Georgalas, Ilias, Markomichelakis, Nikolaos, Vergados, Ioannis, Gianakaki, Emanuela, Rouvas, Alexander
• Format: Report
• Language: English
• Published: 01.01.2013
• ISSN: 1176-6336
• DOI: 10.2147/TCRM.S52161

PURPOSETo present the occurrence of the resolution of vitreomacular traction following intravitreal ranibizumab in two patients with inflammatory choroidal neovascular (CNV) membrane with a background of ocular toxoplasmosis. METHODSInterventional case report. RESULTSA 21-year-old Caucasian woman and a 52-year-old Caucasian man both presented with vitreomacular traction with coexistent classic CNV membrane and a background of ocular toxoplasmosis. They both received an intravitreal injection of ranibizumab in an effort to control the underlying CNV membrane. A resolution of the vitreomacular traction was observed within 1 week of the intravitreal injection in both cases. CONCLUSIONTo the best of our knowledge, this is the first reported case of vitreomacular traction resolution in two patients with ocular toxoplasmosis following ranibizumab administration. Of course, further studies are needed in order to adequately support this association.