Direct transformation of 5-hydroxymethylfurfural to the building blocks 2,5-dihydroxymethylfurfural (DHMF) and 5-hydroxymethyl furanoic acid (HMFA) viaCannizzaro reaction

An efficient, simple, scalable and atom efficient method for the synthesis of 2,5-dihydroxymethylfuran (DHMF) and 5-hydroxymethylfuranoic acid, as sodium salt (HMFA), in 80% yield from 5-hydroxymethylfurfural (HMF) in water using NaOH (0.9 eq.) viaa Cannizzaro reaction is described. Both the buildin...

Full description

Saved in:
Bibliographic Details
Published inGreen chemistry : an international journal and green chemistry resource : GC Vol. 15; no. 10; pp. 2849 - 2853
Main Authors Subbiah, Sowmiah, Simeonov, Svilen P, Esperanca, Jose MSS, Rebelo, Luis Paulo N, Afonso, Carlos AM
Format Journal Article
LanguageEnglish
Published 01.09.2013
Online AccessGet full text

Cover

More Information
Summary:An efficient, simple, scalable and atom efficient method for the synthesis of 2,5-dihydroxymethylfuran (DHMF) and 5-hydroxymethylfuranoic acid, as sodium salt (HMFA), in 80% yield from 5-hydroxymethylfurfural (HMF) in water using NaOH (0.9 eq.) viaa Cannizzaro reaction is described. Both the building blocks DHMF and HMFA were successfully isolated merely using selective crystallisation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Feature-2
ISSN:1463-9262
1463-9270
DOI:10.1039/c3gc40930a