Lithocholic acid-cholesterol interactions in rat liver plasma membrane fractions

This study was designed to elucidate the steps involved in the incorporation of lithocholic acid and the increase in cholesterol in liver plasma membranes after lithocholic acid injection. The data suggest that simultaneous interaction of lithocholic acid and cholesterol, and not prior incorporation...

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Published inBiochimica et biophysica acta, Protein structure and molecular enzymology Vol. 796; no. 3; pp. 345 - 353
Main Authors Yousef, I M, Lewittes, M, Tuchweber, B, Roy, C C, Weber, A
Format Journal Article
LanguageEnglish
Published 01.01.1984
Subjects
cholesterol
lithocholic acid
liver
rats
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Summary:This study was designed to elucidate the steps involved in the incorporation of lithocholic acid and the increase in cholesterol in liver plasma membranes after lithocholic acid injection. The data suggest that simultaneous interaction of lithocholic acid and cholesterol, and not prior incorporation or binding of lithocholic acid to the membrane, may be a prerequisite to cholesterol accumulation in the membrane.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Feature-1
ISSN:0167-4838