Effects of injectable anaesthetics on responses to L-glutamate and on spontaneous synaptic activity in lamprey reticulo-spinal neurons

Intracellular recordings were made from reticulo-spinal cells in the medulla of lamprey ammocoetes; potential changes in response to iontophoretically applied L-glutamate were measured before, during and after the preparation was superfused with anaesthetic solutions. Consideration of the results in...

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Bibliographic Details
Published inBritish journal of pharmacology Vol. 82; no. 3; pp. 659 - 666
Main Authors Cullen, K D, Martin, R J
Format Journal Article
LanguageEnglish
Published 01.01.1984
Subjects
Petromyzon marinus
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Summary:Intracellular recordings were made from reticulo-spinal cells in the medulla of lamprey ammocoetes; potential changes in response to iontophoretically applied L-glutamate were measured before, during and after the preparation was superfused with anaesthetic solutions. Consideration of the results in the light of previous observations on inhibitory responses suggests a basis for some of the excitatory side effects of these compounds, assuming that the equivalent mammalian cells are similarly affected.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0007-1188