Omnipotent suppressors effective in psi super(+) strains of Saccharomyces cerevisiae): Recessiveness and dominance

The authors have characterized recessive and dominant omnipotent suppressor mutations obtained by coreversion of the leu2-1 UAA mutation and the met8-UAG mutation in a psi super(+) strain of Saccharomyces cerevisiae). The sup47 and sup36 suppressors show linkage to the tyr1 locus and the aro1 locus,...

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Published inGenetics (Austin) Vol. 107; no. 2; pp. 219 - 230
Main Authors Ono, B-I, Moriga, N, Ishihara, K, Ishiguro, J, Ishino, Y, Shinoda, S
Format Journal Article
LanguageEnglish
Published 01.01.1984
Subjects
Saccharomyces cerevisiae
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Summary:The authors have characterized recessive and dominant omnipotent suppressor mutations obtained by coreversion of the leu2-1 UAA mutation and the met8-UAG mutation in a psi super(+) strain of Saccharomyces cerevisiae). The sup47 and sup36 suppressors show linkage to the tyr1 locus and the aro1 locus, respectively. Of the suppressors acting dominantly upon both markers, those linked to the tyr1 locus are alleles of the SUP46 ribosomal mutation. The sup47 suppressors differ from the SUP46 suppressors in their suppressor activities in heterozygous diploids, in their map possitions relative to the lyr1 locus and in their effects on the S11 ribosomal protein. The recessive suppressors and the dominant suppressors also differ in their effects on cell growth.
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ISSN:0016-6731