Musculoskeletal pain, profile and quality of life of individuals with sickle cell disease

• Published in: Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil)) Vol. 16; no. 5; pp. 431 - 438
• Main Authors: Ohara, D G, Ruas, G, Castro, S S, Martins, PRJ, Walsh, IAP
• Format: Journal Article
• Language: Portuguese
• Published: 01.10.2012
• Subjects: Arms; Blacks; Chest; Diseases; Economics; Education; Lifestyle; Pain; Surveys
• ISSN: 1413-3555

Background: Sickle cell disease is a prevalent condition in Brazil. Its clinical presentation includes vascular occlusion that result in ischemia, inflammation, dysfunctions, pain and chronic hemolysis, causing irreversible damage and compromising quality of life. Objective: The objectives of this study were to verify the relationship between musculoskeletal pain, from different body parts, with social economic characteristics and quality of life among individuals with sickle cell disease. Method: 27 individuals with sickle cell disease were interviewed with the use of a structured questionnaire with questions about personal, social, economic and cultural variables, the Nordic musculoskeletal symptoms questionnaire and the SF-36 Health Survey. Data were analyzed descriptively using frequencies and percentages. The inferential Chi-Square test was used for dichotomous variables and the Student t- test for continuous variables, with a significance of 5%. A logistic regression was performed using all variables that correlated with pain as dependent variables. Results: The mean age was 31.77 years, predominantly male, black, registered active employment, with average education and income up to three minimum wages. The regions most affected by pain were hip/limbs, chest, lower back and arms. Physical Functioning from the SF-36 had the highest score and mental health the lowest score. Musculoskeletal pain was present in the arms, chest and lower back. Social Functioning was not associated with pain, indicating the influence of other factors. Arm pain was more frequent in black individuals and those with low education. Conclusion: Body pain was associated with race and education and all pain areas were associated with the physical components of the SF-36. Pain was significantly associated with vitality and mental health components of the SF-36.Original Abstract: Contextualizacao: As doencas falciformes constituem um grupo frequente no Brasil. Suas alteracoes ocasionam vaso-oclusao, resultando em isquemia, inflamacao, disfuncoes, dor e hemolise cronica, gerando danos irreversiveis, comprometendo a qualidade de vida. Objetivo: Verificar a relacao entre a dor osteomuscular, considerando sua localizacao corporal, e caracteristicas sociais, economicas e de qualidade de vida em individuos com doenca falciforme. Metodo: Foram coletadas informacoes pessoais, sociais e economicas, alem de dados do Questionario Nordico de Sintomas Osteomusculares (QNSO) e Short Form 36 em 27 individuos. Os dados foram analisados descritivamente por meio de frequencias e porcentagens. A analise inferencial usou o teste do qui-quadrado (variaveis dicotomicas) e t de Student(variaveis continuas), com significancia de 5%. Analises de regressao logistica utilizaram como variaveis dependentes cada uma das que se relacionaram com dor. Resultados: A media de idade foi de 31,77 anos. predominando sexo masculino, negros, emprego ativo, escolaridade media e rendimento inferior a tres salarios minimos. Quadril/membros inferiores. regiao dorsal, lombar e bracos foram mais acometidos pela dor. A capacidade funcional apresentou o maior valor, e saude mental, o menor. Aspectos fisicos foram comprometidos pela dor nos bracos. coluna dorsal e lombar. Aspectos sociais nao se associaram com a dor. indicando influencia de outros fatores. A dor nos bracos foi mais frequente entre os negros e os com baixa escolaridade. Conclusao: A dor nas regioes corporais analisadas relacionou-se com a raca e a escolaridade e com todos os dominios referentes ao componente fisico do SF-36. Os componentes vitalidade e saude mental apresentaram associacao significativa com a dor.