Onychomycosis: Multicentre epidemiological, clinical and mycological study
Background: Onychomycosis accounts for up to 50% of all nail disorders. They can be caused by: yeasts, dermatophytes and non-dermatophyte moulds. Objectives and methods: A multicentre study designed to determine the prevalence, mycological test results, aetiological agents, and clinical presentation...
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Published in | Revista iberoamericana de micología Vol. 29; no. 3; pp. 157 - 163 |
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Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | Spanish |
Published |
01.07.2012
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Subjects | |
Online Access | Get full text |
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Summary: | Background: Onychomycosis accounts for up to 50% of all nail disorders. They can be caused by: yeasts, dermatophytes and non-dermatophyte moulds. Objectives and methods: A multicentre study designed to determine the prevalence, mycological test results, aetiological agents, and clinical presentation of onychomycosis was carried out. All fingernail and toenail samples taken during a one year period at 9 diagnostic centres were included. Results: A total of 5,961 samples were analysed, of which 82.3% were from toenails and 17.7% from fingernails. The mean age of the patients was 49.7 years, and 66% were females. Direct microscopic examination was positive in 61% of the samples. In adults, 61.2% of toenails were positive using potassium hydroxide (KOH), and 43.7% were positive in cultures. The prevailing aetiological agents belong to the dermatophyte group (82.8%), and distal subungual was the most common clinical form. In fingernails, direct examination showed 59.8% positive samples, and cultures were positive in 52.9%. The prevailing agents were yeasts belonging to Candida species, and onycholysis was the most common lesion. Conclusions: Direct mycological examinations were positive in 61%, a higher value than that found in other series. Dermatophytes were prevalent in toenails of both sexes, and in finger nails yeast were prevalent in females, and dermatophytes in males. Non-dermatophyte moulds corresponded to 4.8% of toenail and 2.05% of fingernails isolates.Original Abstract: Antecedentes: Las onicomicosis representan aproximadamente el 50% de las onicopatias, pueden ser causadas por dermatofitos. levaduras u hongos filamentosos no dermatofitos. Objetivos y metodologia: Se realizo un estudio multicentrico para conocer la prevalencia de onicomicosis, los agentes causales y las formas clinicas mas frecuentes. Se evaluaron todas las muestras de unas de manos y pies durante el periodo de un ano en 9 centros asistenciales. Resultados: Se procesaron 5.961 muestras, el 82,3% correspondieron a unas de pies y el 17,7% a unas de manos. La edad promedio de los pacientes fue 49,7 anos y el 66% pertenecid al sexo femenino. Los examenes directos fueron positivos en el 61% de los casos. En adultos, las unas de los pies presentaron un 61,2% de resultados positivos en el examen directo, y los cultivos fueron positivos en un 43,7%. Los hongos predominances fueron ios dermatofitos (82,8%) y la forma ciinica mas frecuente fue la distal subungueal. En unas de manos la positividad del examen directo fue del 59,8% y los cultivos fueron positivos en un 52,9%; los hongos predominantes fueron de tipo levaduriforme y la forma clinica mas frecuente fue la onicolisis. Conclusiones: Se encontro un 61% de positividad en el examen directo, valor superior al de otras investigaciones. En las unas de los pies prevalecieron los dermatofitos en ambos sexos, y en unas de manos las levaduras, en el sexo femenino, y dermatofitos, en el masculino. El 4,8% de los aislamientos de unas de pies y el 2,05% de los de unas de manos fueron de hongos filamentosos no dermatofiticos. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-1 |
ISSN: | 1130-1406 |
DOI: | 10.1016/j.riam.2011.11.003 |