Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS sub(3)PE) Syndrome Accompanied by Parkinson's Disease

• Published in: Internal medicine (Tokyo, 1992) Vol. 46; no. 14; pp. 1139 - 1142
• Main Authors: Ito, Eiichi, Okamoto, Hiroshi, Mochizuki, Atsuko, Ohara, Kuniko, Kato, Maiko, Terashima, Yutaka, Tanaka, Eiichi, Takagi, Kae, Uchiyama, Shinichiro, Iwata, Makoto
• Format: Journal Article
• Language: English
• Published: 01.01.2007
• ISSN: 1349-7235
• DOI: 10.2169/internalmedicine.46.0029

We encountered two cases of RS sub(3)PE (remitting seronegative symmetrical synovitis with pitting edema) syndrome accompanied by Parkinson's disease (PD). Although the etiology of RS sub(3)PE syndrome is still unknown, several possible associations, such as malignancies and viral infections, have been reported; RS sub(3)PE syndrome is thought to be an autoimmune-mediated disorder. The present patients did not have any factors which are reported to be associated with RS sub(3)PE. Whether or not the complication of PD and RS sub(3)PE syndrome is incidental needs to be further examined, and we discuss here the possible cause of association between PD and RS sub(3)PE syndrome, including dopamine agonists one of the anti-PD medications.