Ministry of Health National Antimicrobial Resistant Investigation Net 2010 report: Bacterial distribution and resistance analysis in north of China

• Published in: Zhongguo lin chuang yao li xue za zhi Vol. 27; no. 12; pp. 932 - 939
• Main Authors: Ai, X-M, Tao, F-R, Xu, H-T, Chen, D-K, Zhang, X-Z, Hu, Y-J
• Format: Journal Article
• Language: English
• Published: 28.12.2011
• Subjects: Acinetobacter; Ampicillin; Antibiotics; Antimicrobial agents; Cerebrospinal fluid; Clinical isolates; Cocci; Drug resistance; Escherichia coli; Hospitals; Imipenem; Influenza; Linezolid; Meropenem; Methicillin; Microorganisms; Penicillin; Pneumonia; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus pneumoniae; Teicoplanin; Vancomycin
• ISSN: 1001-6821

Objective To investigate the resistance of clinical isolates from hospitals in north China in 2010. Methods Bacterial susceptibility testing was carried out according to an agreed protocol and standard. The results were analyzed by WHONET 5.6. Results A total of 50277 clinical isolates were collected from January to December 2010, of which gram negative microorganisms and gram positive cocci accounted for 67.8% and 32.3%, respectively. Methicillin resistant strains in S. aureus (MRSA) and MRSCON accounted for an average 50.6% and 83.4% respectively. No S. aureus isolates were found resistant to vancomycin, teicoplanin and linezolid. There are 0.6% and 0.1% of E. faecalis and 8.2% and 3.6% of E. faecium strains resistant to vancomycin and teicoplanin respectively. In the 375 strains of S. pneumoniae, 88.7% were identified as penicillin resistant S. pneumonia (PRSP) respectively if used the standard of in cerebrospinal fluid (CSF), if used the non - in CSF, 6.5% were identified as PRSP. There were 31.9% of 347 isolates of H. influenza resistances to ampicillin. There were 5.7% E. coli strains resistant to imipenem and 9.8% K. pneumonia strains resistant to imipenem. Pseudomonas aeruginosa and Acinetobacter baumanii resistanted to imipenem and meropenem were 28.3% and 56.5%. Conclusion Bacterial resistance was still on the rise in north China, and it was very important to reasonable application antibiotics and prevents the dissemination and outbreak of pan - resistant bacteria.