sup 1^H, ^sup 13^C, and ^sup 15^N resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis

The AbrB protein is a transcription factor that regulates the expression of numerous essential genes during the cells transition phase state. AbrB from Bacillus anthracis is, nototriously, the principal protein responsible for anthrax toxin gene expression and is highly homologous to the much-studie...

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Bibliographic Details
Published inBiomolecular NMR assignments Vol. 6; no. 1; p. 95
Main Authors Olson, Andrew L, Bobay, Benjamin G, Melander, Christian, Cavanagh, John
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Nature B.V 01.04.2012
Subjects
Bacteria
Cells
Gene expression
NMR
Nuclear magnetic resonance
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Summary:The AbrB protein is a transcription factor that regulates the expression of numerous essential genes during the cells transition phase state. AbrB from Bacillus anthracis is, nototriously, the principal protein responsible for anthrax toxin gene expression and is highly homologous to the much-studied AbrB protein from Bacillus subtilis having 85% sequence identity and the ability to regulate the same target promoters. Here we report backbone and sidechain resonance assignments and secondary structure prediction for the full-length AbrB protein from B. anthracis.[PUBLICATION ABSTRACT]
ISSN:1874-2718
1874-270X
DOI:10.1007/s12104-011-9333-2