Meningoensafaliti Taklit Eden Akut Izoniazid Zehirlenmesi: Olgu Sunumu ve Literatürün Gözden Geçirilmesi/Acute Isoniazid Poisoning Mimicking Meningoencephalitis: Case Report and Review of Literature

Antituberculosis drug-induced intoxications, though at a diminished level, could still rarely occur in the present day. Isoniazid-induced seizures, hepatotoxicity, and neurotoxicity have been reported, usually as chronic side effects. In the present study, we report a case who was brought to our hos...

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Bibliographic Details
Published inEurasian journal of emergency medicine Vol. 10; no. 1; p. 43
Main Authors Köse, Ataman, Zenginol, Murat, Köse, Beril, Günay, Nurullah, Yildirim, Cuma
Format Journal Article
LanguageTurkish
Published Ankara Galenos Publishing House 01.03.2011
Subjects
Antibiotics
Convulsions & seizures
Toxicity
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Summary:Antituberculosis drug-induced intoxications, though at a diminished level, could still rarely occur in the present day. Isoniazid-induced seizures, hepatotoxicity, and neurotoxicity have been reported, usually as chronic side effects. In the present study, we report a case who was brought to our hospital unconscious with meningoencephalitis and who, following prolonged prognosis efforts, was determined to have developed neurotoxicity, recurring seizures, and hepatotoxicity due to attempted suicide by ingestion of a potentially lethal dose (300 mg INH*50 tablets; 15 gr) of isoniazid. [PUBLICATION ABSTRACT]
ISSN:2149-5807
2149-6048