Enzymatic production of 18-[beta]-glycyrrhetinic acid from Glycyrrhizaglabra L

Enzymatic conversion of glycyrrhizinic acid (GL), from root extract of Glycyrrhiza glabra L., into 18-β-glycyrrhetinic acid (GA) was achieved by using a commercial preparation of β-glucuronidase from Aspergillus niger. Two different processes were tested: a batch process and a continuous process. Th...

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Bibliographic Details
Published inBiotechnology letters Vol. 24; no. 22; p. 1907
Main Authors Morana, Alessandra, Lazzaro, Antonella Di, Lernia, Isabella Di, Ponzone, Cesare, De Rosa, Mario
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Nature B.V 01.11.2002
Subjects
Enzymatic activity
Enzymes
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Summary:Enzymatic conversion of glycyrrhizinic acid (GL), from root extract of Glycyrrhiza glabra L., into 18-β-glycyrrhetinic acid (GA) was achieved by using a commercial preparation of β-glucuronidase from Aspergillus niger. Two different processes were tested: a batch process and a continuous process. The continuous process was the better one, giving 100% conversion of GL after 5 d and 80% recovery of enzyme activity. The process yielded a product containing 40% GA.[PUBLICATION ABSTRACT]
ISSN:0141-5492
1573-6776
DOI:10.1023/A:1020904325906