The Contribution of Interleukin-12/Interferon-[gamma] Axis in Protection Against Neonatal Pulmonary Chlamydia muridarum Challenge

• Published in: Journal of interferon & cytokine research Vol. 30; no. 6; p. 407
• Main Authors: Jupelli, Madhulika, Selby, Dale M, Guentzel, M Neal, Chambers, James P, sthuber, Thomas G, Zhong, Guangming, Murthy, Ashlesh K, Arulanandam, Bernard P
• Format: Journal Article
• Language: English
• Published: New Rochelle Mary Ann Liebert, Inc 01.06.2010

Neonatal Chlamydia trachomatis pneumonia has been associated with respiratory sequelae in later life. We recently established a mouse model of neonatal pulmonary Chlamydia muridaum infection and found an important contribution of IFN-γ to protective immunity. In this study, we further characterized...