IGG-RBD RESPONSE TO INACTIVATED SARS-COV-2 VACCINE

SARS-CoV-2 activates the coagulation system together with the immune response and this study aimed to examine the immunoglobulin G-receptorbinding domain (IgG-RBD) response and changes in fibrinogen and D-dimer concentrations in individuals who were previously infected with coronavirus or vaccinated...

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Bibliographic Details
Published inRomanian archives of microbiology and immunology Vol. 81; no. 3; p. 242
Main Author Rădulescu, Elena-Diana
Format Journal Article
LanguageEnglish
Published Bucharest Institutul Cantacuzino 01.07.2022
Subjects
Age groups
Antibodies
Antibody response
Autoimmune diseases
Cardiovascular disease
Cardiovascular diseases
Chronic obstructive pulmonary disease
Comorbidity
Coronaviruses
COVID-19 vaccines
Diabetes mellitus
Fibrinogen
Hypertension
Hyperthyroidism
Immune response
Immunoglobulin G
Proteins
Severe acute respiratory syndrome coronavirus 2
Vaccines
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Summary:SARS-CoV-2 activates the coagulation system together with the immune response and this study aimed to examine the immunoglobulin G-receptorbinding domain (IgG-RBD) response and changes in fibrinogen and D-dimer concentrations in individuals who were previously infected with coronavirus or vaccinated following the first and second doses of inactivated CoronaVac vaccine. For the evaluation of age and comorbidities related to the antibody response, the subjects were classified into three age groups and five comorbidities groups were considered: hypertension and cardiovascular disease, diabetes mellitus, asthma/COPD, hypo-/hyperthyroidism, and other autoimmune diseases. [...]the protective efficacy and duration of efficacy remain controversial for CoronaVac. * Kaytaz M, Akkaya E, Gumus SN, Genc S, Issever H, Omer B. IgG-RBD Response Due to Inactivated SARS-CoV-2 Vaccine: Alteration in D-Dimer and Fibrinogen Concentrations, Association with Comorbidities and Adverse Effects.
ISSN:1222-3891
2601-9418