Impact of air pollutants on genome stability and health-related biomarkers

Efforts to reduce air pollution involve regulations, technological advancements, and promoting sustainable practices to mitigate its impact on both human health and the environment. [...]we aimed to explore how air pollution can affect genomic instability and consequently our health by determining p...

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Published inArhiv za higijenu rada i toksikologiju Vol. 74; no. 4; p. A68
Main Authors Gajski, Goran, Gerić, Marko, Pehnec, Gordana, Matković, Katarina, Milić, Mirta, Kašuba, Vilena, Delić, Luka, Jurič, Andreja, Karačonji, Irena Brčić, Jakovljević, Ivana, Davila, Silvije, Rinkovec, Jasmina, Codec, Ranka, Žužul, Silva, Bešlić, Ivan, Domijan, Ana-Marija, Cvitković, Ante, Sanković, Mandica, Šumanovac, Antun, Wild, Pascal, Cann, Irina Guseva, Hopf, Nancy B
Format Journal Article
LanguageEnglish
Published Zagreb Institute for Medical Research and Occupational Health 01.10.2023
Subjects
Air pollution
Animal models
Biocompatibility
Biomarkers
Biomonitoring
Cell culture
Chemical agents
Genomic instability
In vitro methods and tests
In vivo methods and tests
Outdoor air quality
Pollutants
Pollution control
Sustainable practices
Toxicology
Croatia
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Summary:Efforts to reduce air pollution involve regulations, technological advancements, and promoting sustainable practices to mitigate its impact on both human health and the environment. [...]we aimed to explore how air pollution can affect genomic instability and consequently our health by determining possible associations between air pollutants and biomarkers of exposure and effects. Given the transboundary nature of air pollution, our results might be regionally important. Since air pollution is considered a significant health issue, and air pollution is often site-specific, more studies using biomarkers of exposure, as well as using different biomarkers of effect could be expected. In the field of genetic toxicology, he uses various methodological approaches, both in vitro and in vivo, on different cell and animal models to investigate the effects of various physical and chemical agents on organisms, tissues, cells, and cell structures with special emphasis on the DNA molecule. [...]the scope of his work also comprises human biomonitoring studies in different environmental and occupational settings.
ISSN:0004-1254
1848-6312