Human amniotic membrane accelerates healing in a hard-to-heal diabetic foot ulcer

Human amniotic membrane (HAM) is acquired from the human placenta. This advanced regenerative therapy rich in growth factors, stem cells and cytokines, limits the extent of continuing inflammatory damage, decreases the microbial bioburden, and promotes progression into the proliferative phase of hea...

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Bibliographic Details
Published inWound healing southern Africa Vol. 16; no. 1; p. 27
Main Author Idensohn, P J
Format Journal Article
LanguageEnglish
Published Pretoria Medpharm Publications 01.06.2023
Subjects
Case reports
Debridement
Diabetes
Foot diseases
Glucose monitoring
Growth factors
Infections
Leg ulcers
Pain
Silicones
Skin & tissue grafts
Stem cells
Wound healing
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Summary:Human amniotic membrane (HAM) is acquired from the human placenta. This advanced regenerative therapy rich in growth factors, stem cells and cytokines, limits the extent of continuing inflammatory damage, decreases the microbial bioburden, and promotes progression into the proliferative phase of healing.¹ HAM provides a natural cellular scaffold for cellular adhesion facilitating keratinocyte migration to promote reepithelialisation and enable remodelling to accelerate wound healing.¹ High quality studies with good evidence specify the safe and effective use of HAM in the management of diabetic foot ulcers.²,³
ISSN:1998-8885
2076-8893