Re-evaluating evidence for adaptive mutation rate variation/Reply

• Published in: Nature (London) Vol. 619; no. 7971; pp. E52 - 2
• Main Authors: Wang, Long, Ho, Alexander T, Hurst, Laurence D, Yang, Sihai
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group 27.07.2023
• Subjects: Clustering; Genes; Genomes; Heterogeneity; Mutation; Mutation rates

[...]failure to eliminate poor-quality reads and mapping artefacts will overreport clustering of putative mutations. In neither, nor in the merged dataset, is there heterogeneity in the mutation rate between gene classes in coding sequence (CDS) or intron (Fig. 1b and Extended Data Fig. 2). The most...