Clinical Study on the Retention Enema with Modified Dahuang Mudan Decoction in Treating Lower-Jiao Obstruction Syndrome Caused by Severe Pneumonia Complicated with Heart Failure

• Published in: Medicinal plant Vol. 13; no. 5; pp. 62 - 65
• Main Authors: Du, Yaonan, Zhao, Peilin, Li, Bo, Tian, Jing, Xu, Shihong, Pu, Zhongxin
• Format: Journal Article
• Language: English
• Published: Cranston Wu Chu (USA-China) Science and Culture Media Corporation 01.10.2022
• Subjects: Arrhythmia; Autoimmune diseases; Blood; Blood coagulation; Brain natriuretic peptide; C-reactive protein; Cardiac function; Cardiovascular disease; Chinese medicine; Congestive heart failure; Constipation; Creatinine; Diuretics; Drugs; Edema; Endocrine disorders; Heart failure; Hypothermia; Infectious diseases; Intestine; Liver; Malabsorption; Mechanical ventilation; Mortality; Multiple organ dysfunction syndrome; Myocardial infarction; Peptides; Pneumonia; Procalcitonin; Respiration; Retention; Sepsis; Septic shock; Thorax; Transaminase; Tumors; Ventilation; Ventilators
• ISSN: 2152-3924
• DOI: 10.19600/j.cnki.issn2152-3924.2022.05.014

The treatment group was treated with Modified Dahuang Mudan Decoction on the basis of conventional treatment for 7 d. The efficacy indicators and adverse events such as white blood count (WBC) , C-reactive protein (CRP) , procalcitonin (PCT) , N-terminal pro-brain natriuretic peptide (NT-proBNP) , Lausanne Intestinal Failure Estimation (LIFE) and multiple organ dysfunction score (MODS) were observed. The results are reported as follows. 2 Data and methods 2.1 Diagnostic criteria of Western medicine (i) The diagnostic criteria of severe pneumonia put forward by the American Association of Infectious Diseases/American Thoracic Society, that is, the main criteria; invasive mechanical ventilation is required , and septic shock needs vasoconstrictor treatment; secondary criteria & respiratory rate & 30/min, oxygenation indicators < 250, hypothermia (< 36. 4 Exclusion criteria Respirator depression or respirator and cardiac arrest; malignant arrhythmia and acute myocardial infarction ; accompanied by malignant tumor or tuberculosis; severe liver and kidney damage (glutamic pyruvic transaminase in liver function >3 times ULN (upper limit of normal value) , serum creatinine > 2 times ULN (upper limit of normal value) ; severe endocrine diseases, autoimmune diseases, inflammator or malabsorption bowel diseases; abnormal blood coagulation and bleeding tendency; paricipate in other researchers in recent 2 months. 2.5 Generation and concealment of randomized plan RCT was adopted in this study, and SPSS 19.0 statistical software was used to generatt random number table. 2.8 Observation indicators White blood cell (WBC) , C-reactive protein (CRP), procalcitonin (PCT), N-terminal probrain natriuretic peptide (NT-prBNP) , Lausanne Intestinal FailureEstimation (LIFE)