STABILIREA VALORILOR DE REFERINȚĂ ALE UNOR PARAMETRI BIOLOGICI PENTRU ANIMALELE DE LABORATOR DIN STAȚIUNEA BĂNEASA

In order to evaluate the health and well-being of the animals in this study, the aim was to compare the results of biochemical and hematological parameters of laboratory animals raised in SPF (Specific Pathogen Free) conditions with those working on conventional experimental premises. The results ob...

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Published inRomanian archives of microbiology and immunology Vol. 81; pp. 71 - 72
Main Authors Petronica, Gheorghiu, Angelica, Dinu, Larisa, Ancuţa Diana, Fabiola, Ioniţă, Cristin, Coman, Crina, Stăvaru
Format Journal Article
LanguageEnglish
Romanian
Published Bucharest Institutul Cantacuzino 01.11.2022
Subjects
Hematology
Laboratory animals
Pathogens
Specific pathogen free
Statistical analysis
New Zealand
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Summary:In order to evaluate the health and well-being of the animals in this study, the aim was to compare the results of biochemical and hematological parameters of laboratory animals raised in SPF (Specific Pathogen Free) conditions with those working on conventional experimental premises. The results obtained showed that there are no statistically significant differences between the animals housed in SPF conditions and those housed in conventional conditions or in the experimental areas, which demonstrates the maintenance of normal health status. The hematological and biochemical determinations are required to be performed periodically to check the welfare of the laboratory animal heards in the Băneasa Animal Facility, aiming both to obtain reference values at the facility level and to demonstrate the welfare conditions of the animals in the experiments.This is an important step in the development of an accredited preclinical testing unit.
ISSN:1222-3891
2601-9418