Natural polymers: Best carriers for improving bioavailability of poorly water soluble drugs in solid dispersions

Natural polymers and its modified forms can be used as best alternative for improving bioavailability of poorly water soluble drugs in solid dispersion. Most of the natural polymers are hydrophilic and having high swelling capacity. Recent trend towards the use of natural polymer demands the replace...

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Bibliographic Details
Published inMarmara Pharmaceutical Journal Vol. 17; no. 2; p. 65
Main Authors Sapkal, Sandip, Narkhede, Mahesh, Babhulkar, Mukesh, Mehetre, Gautam, Rathi, Ashish
Format Book Review
LanguageEnglish
Published Istanbul Marmara University 01.01.2013
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Summary:Natural polymers and its modified forms can be used as best alternative for improving bioavailability of poorly water soluble drugs in solid dispersion. Most of the natural polymers are hydrophilic and having high swelling capacity. Recent trend towards the use of natural polymer demands the replacement of synthetic additives with natural ones. Many plant derived natural polymers are studied for use in solid dispersion systems, out of which natural gums, cyclodextrin and carbohydrate are most extensively studied and used. This review discusses about the majority of these natural polymers, its uses and some recent investigations about modification of natural polymer in solid dispersion systems.
ISSN:2630-6344
2630-6344