Detection of Antibodies in Patients with COVID-19 by Rapid Chromatographic Immunoassay COVID-19

Objective: Coronavirus disease-2019 (COVID-19) is a potentially fatal respiratory disease caused by SARS-CoV-2, which has occurred in a human pandemic. This study aims to assess the responses of IgM and IgG antibodies to the virus after 7-14 days following the onset of illness. Materials and Methods...

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Published inTurkish journal of immunology : the official journal of the Turkish Society of Immunology Vol. 10; no. 2; p. 115
Main Authors Ali, Abubaker H, Zidan, Ali S
Format Journal Article
LanguageEnglish
Published Istambul Turkish Society of Immunology 01.01.2022
Subjects
Antibodies
Chromatography
Coronaviruses
COVID-19
Immunoassay
Immunoglobulin G
Immunoglobulin M
Respiratory diseases
Severe acute respiratory syndrome coronavirus 2
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Summary:Objective: Coronavirus disease-2019 (COVID-19) is a potentially fatal respiratory disease caused by SARS-CoV-2, which has occurred in a human pandemic. This study aims to assess the responses of IgM and IgG antibodies to the virus after 7-14 days following the onset of illness. Materials and Methods: A total of 95 cases, including 67 patients with COVID-19 (24 male and 43 female) and 28 healthy individuals without COVID-19 as the control group (7 male and 21 female), were selected in the present study. IgM and IgG antibodies for COVID-19 were evaluated using rapid chromatographic immunoassay (RCI). Results: RCI demonstrated that IgM antibody was found as positive in 67 patients (100%) after 7-14 days, whereas IgG antibody was found as positive in 56 patients (83.6%) after 7 days and 67 patients (100%) were positive after 14 days. Conclusion: According to the obtained results, RCI for IgM and IgG antibodies can be used to make a quick and accurate diagnosis of COVID-19 infections.
ISSN:1301-109X
2147-8325
DOI:10.4274/tji.galenos.2022.26349