Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)

Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic t...

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Published inCase Reports in Gastroenterology pp. 320 - 325
Main Authors Jukic, Ivana, Bozic, Dorotea, Lalovac, Milos, Mirela Pavicic Ivelja, Radic, Mislav, Sundov, Zeljko, Vukovic, Jonatan
Format Report
LanguageEnglish
Published Basel S. Karger AG 23.05.2022
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Summary:Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic thrombosis associated with COVID-19 infection and methylenetetrahydrofolate reductase gene polymorphism (C677T) treated with rivaroxaban resulting in acute liver failure with fatal outcome.
DOI:10.1159/000524791