Cardiocerebral Effects on the Temporal Organization of Blood Pressure in Patients with Multiple Sclerosis Living in the North

The pathogenesis of comorbid cardiovascular complication worsens the course and prognosis of multiple sclerosis (MS), and the possible involvement of a vascular factor in the pathogenesis of MS, confirmed by neuroimaging. According to neuroimaging of the brain in older patients, more than 45 years,...

Full description

Saved in:
Bibliographic Details
Published inWorld heart journal Vol. 13; no. 1; pp. 141 - 143
Main Authors Molchanova, Zh I, Ragozin, O N, Al-Bawareed, Omar
Format Journal Article
LanguageEnglish
Published Hauppauge Nova Science Publishers, Inc 01.01.2021
Subjects
Age
Blood pressure
Cardiovascular system
Circadian rhythm
Comorbidity
Disease
Family medical history
Heart rate
Hypertension
Medical imaging
Multiple sclerosis
Nervous system
Obesity
Paresis
Pathogenesis
Risk factors
Womens health
Russia
Online AccessGet full text

Cover

More Information
Summary:The pathogenesis of comorbid cardiovascular complication worsens the course and prognosis of multiple sclerosis (MS), and the possible involvement of a vascular factor in the pathogenesis of MS, confirmed by neuroimaging. According to neuroimaging of the brain in older patients, more than 45 years, with a history of vascular disease, in addition to demyelination, focal microcirculation disorders are also detected, similar to changes in patients with cerebrovascular diseases. Organic damage to the descending autonomic pathways in the brain stem and spinal cord may lead to deteriorations of the functions of the autonomous nervous system, such as a decrease in heart rate variability. Chronic stress associated with this pathology leads to hyperreactivity of the hypothalamic- pituitary-adrenal axis, which predisposes to an increase in blood pressure (BP). Medications used in recent decades that change the course of MS can also have adverse effects associated with the cardiovascular system. There is evidence from the Northern region that cardiovascular diseases occur at an earlier age and have a high prevalence among people of working age. Here, Molchanova et al examine the temporal organization of BP in MS patients living in the Northern region.
ISSN:1556-4002
2577-6584