AVIBACTAM-CONTAINING ANTIMICROBIAL COMBINATIONS AGAINST CARBAPENEM-RESISTANT ENTEROBACTERALES

The global prevalence of drug-resistant pathogens that have evolved novel antimicrobial resistance mechanisms continues to pose a challenge to our capacity to manage infections. Investigation of the carbapenem resistance mechanisms was carried out for each isolate, through the use of the modified ca...

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Bibliographic Details
Published inRomanian archives of microbiology and immunology Vol. 79; no. 4; p. 307
Main Author Florea, Carmen Ana Isabelle
Format Journal Article
LanguageEnglish
Published Bucharest Institutul Cantacuzino 01.10.2020
Subjects
Antibiotics
Antimicrobial agents
Antimicrobial resistance
Carbapenemase
Drug resistance
E coli
β Lactamase
South Korea
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Summary:The global prevalence of drug-resistant pathogens that have evolved novel antimicrobial resistance mechanisms continues to pose a challenge to our capacity to manage infections. Investigation of the carbapenem resistance mechanisms was carried out for each isolate, through the use of the modified carbapenem inactivation method, PCR and the MicroScan ESBL detection test. The authors recognize several limitations of the study: only carbapenemase and ß-lactamase-related resistance was examined. [...]only E. coli and K. pneumoniae strains were selected for the purpose of the study.
ISSN:1222-3891
2601-9418