Sarcopenia is associated with hypertension in older adults: a systematic review and meta-analysis

Background: Sarcopenia and handgrip strength have been observed and correlated in association with hypertension among the old-age people. However, the results reported in different studies were inconsistent. In the current study, we conducted a systematic review and meta-analysis to reveal the signi...

Full description

Saved in:
Bibliographic Details
Published inBMC Geriatrics
Main Authors Bai, Tingting, Fang, Fang, Li, Feika, Ren, Yan, Hu, Jiaan, Cao, Jiumei
Format Book Review
LanguageEnglish
Published Durham Research Square 30.03.2020
Subjects
Hypertension
Older people
Sarcopenia
Systematic review
Online AccessGet full text

Cover

More Information
Summary:Background: Sarcopenia and handgrip strength have been observed and correlated in association with hypertension among the old-age people. However, the results reported in different studies were inconsistent. In the current study, we conducted a systematic review and meta-analysis to reveal the significant association between sarcopenia, handgrip strength, and hypertension in older adults. Methods: PubMed, MEDLINE, Cochrane Library, and EMBASE databases were searched from inception to 15 November, 2019 to retrieve the original research studies that addressed the association between sarcopenia, handgrip strength, and hypertension. All the relevant data were retrieved, analyzed, and summarized. Results: 19 studies met the inclusion criteria and a total of 21301 participants were included in the meta-analysis. Eight eligible studies have reported the odd ratios (ORs) of hypertension and the ORs ranged from 0.41 to 4.38. When pooled the ORs together, the summarized ORs was 1.29 95% confidence interval (CI) =1.00-1.67. The summarized ORs for the Asian group 1.50 (95% CI=1.35-1.67) was significantly higher than that of Caucasian group 1.08 (95% CI=0.39-2.97). Eleven studies have provided the data on association between handgrip strength and hypertension. The overall ORs and 95% CI was 0.99 (95% CI=0.80-1.23), showing no significant association. Conclusion: Sarcopenia was associated with hypertension, but no correlation was found between handgrip strength and hypertension in older adults.