A boronic acid modified binary matrix consisting of boronnitride and α-cyano-4-hydroxycinnamic acid for determination of cis-diols by MALDI-TOFMS

A MALDI-TOF mass spectrometric method is described for the determination of small molecule compounds with cis-diol. It is based on the use of a binary matrix consisting of boron nitride (BN) and α-cyano-4-hydroxycinnamic acid that was modified with the derivatization reagent of (3-(acridin-9-ylamino...

Full description

Saved in:
Bibliographic Details
Published inMikrochimica acta (1966) Vol. 186; no. 8
Main Authors Ya-Shun, Chen, Hua-Ming, Xiao, Tian-Qi, Wang, Yu, Lei, Yu-Qi, Feng
Format Journal Article
LanguageEnglish
Published Heidelberg Springer Nature B.V 01.08.2019
Subjects
Acids
Boron nitride
Diols
Hydroxycinnamic acid
Ions
Positive ions
Reagents
Spectrometry
Online AccessGet full text

Cover

More Information
Summary:A MALDI-TOF mass spectrometric method is described for the determination of small molecule compounds with cis-diol. It is based on the use of a binary matrix consisting of boron nitride (BN) and α-cyano-4-hydroxycinnamic acid that was modified with the derivatization reagent of (3-(acridin-9-ylamino)phenyl)boronic acid which can recognize cis-diols. The binary matrix is used for desorption/ionization (DI) in the positive ion mode. The mechanism leading to DI enhancement was investigated. The results imply that BN is beneficial for the DI because it induces an enhancement in the positive ion mode. The boronic acid-functionalized binary matrix was successfully applied to capture the glucose, shikimic acid and quinic acid. The method was applied to the determination of 3-chloro-1,2-propanediol in plant oil.
ISSN:0026-3672
1436-5073
DOI:10.1007/s00604-019-3711-3