Correct answer to the quiz. Check your diagnosis Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) with superimposed 5q-syndrome

Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) is a rare entity belonging to myeloproliferative/myelodysplastic syndromes. Myelodysplastic syndrome (MDS) with isolated del(5q) is a category of MDS characterized by better prognosis and specific morphology....

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Published inPolish journal of pathology Vol. 61; no. 2; p. 105
Main Authors Ziarkiewicz, Mateusz, Dwilewicz-Trojaczek, Jadwiga, Pastwińska, Anna, Chmarzyńska, Elżbieta, Paszkowska-Kowalewska, Małgorzata, Koperski, Łukasz, Wiesław Wiktor Jędrzejczak, Ziarkiewicz-Wróblewska, Bogna
Format Journal Article
LanguageEnglish
Published Warsaw Termedia Publishing House 01.01.2010
Subjects
Anemia
Biopsy
Bone marrow
Leukemia
Morphology
Mutation
Neutrophils
Tumors
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Summary:Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) is a rare entity belonging to myeloproliferative/myelodysplastic syndromes. Myelodysplastic syndrome (MDS) with isolated del(5q) is a category of MDS characterized by better prognosis and specific morphology. Herein we describe a 69-year-old male with anaemia and thrombocytosis presenting with coexisting features of both these rare diseases. After the description of the clinical data, we summarize the histopathologic, cytogenetic and molecular findings, as well as introduced treatment. Next, we discuss possible diagnostic options with reference to the relevant literature.
ISSN:1233-9687
2084-9869