DICLOFENAC SPONGIOUS MATRICES BASED ON COLLAGEN AND ALGINATE FOR RELIEVINGIN JURY PAINS

The sport injuries become more and more frequent so there is a need to discover new solutions for increasing the quality of life for people affected by such wounds. The aim of this study was to obtain a novel NSAID drug delivery system, topical diclofenac spongious matrices based on collagen and alg...

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Published inInternational Conference on Advanced Materials and Systems (ICAMS) pp. 75 - 80
Main Authors Drăghici, Roxana-Denisa, Marin, Maria Minodora, Ghica, Mihaela Violeta, Kaya, Mădălina Georgiana Albu, Anuta, Valentina, Dinu-Pîrvu, Cristina, Kaya, Durmuş Alpaslan, Coară, Gheorghe, Albu, Luminiţa, Chelaru, Ciprian
Format Conference Proceeding
LanguageEnglish
Published Bucharest The National Research & Development Institute for Textiles and Leather - INCDTP 01.01.2018
Subjects
Acids
Biocompatibility
Collagen
Drug delivery systems
Hydrogels
Injuries
Nonsteroidal anti-inflammatory drugs
Pain
Rheology
Skin
Sodium
Viscosity
Germany
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Summary:The sport injuries become more and more frequent so there is a need to discover new solutions for increasing the quality of life for people affected by such wounds. The aim of this study was to obtain a novel NSAID drug delivery system, topical diclofenac spongious matrices based on collagen and alginate for the treatment of injuries and relieving of pain. The samples were analyzed by flow analysis and after their freeze-drying were analyzed by FT-IR and in vitro release of sodium diclofenac.The results obtained from analyses confirmed that diclofenac spongious matrices based on collagen and alginate exhibit proper characteristics for the treatment of injuries and relieving of pain.
ISSN:2068-0783
DOI:10.24264/icams-2018.1.10