Antisense oligonucleotide to PKC-sigma alters cAMP-dependent stimulation of CFTR in Calu-3 cells

Protein kinase C (PKC) regulates cystic fibrosis transmembrane conductance regulator (CFTR) channel activity but the PKC signaling mechanism is not yet known. The goal of these studies was to identify PKC isotype(s) required for control of CFTR function.

Saved in:
Bibliographic Details
Published inAmerican Journal of Physiology: Cell Physiology Vol. 44; no. 5; p. C1357
Main Authors Liedtke, Carole M, Cole, Thomas S
Format Journal Article
LanguageEnglish
Published Bethesda American Physiological Society 01.11.1998
Subjects
Anatomy & physiology
Cellular biology
Proteins
Online AccessGet full text

Cover

More Information
Summary:Protein kinase C (PKC) regulates cystic fibrosis transmembrane conductance regulator (CFTR) channel activity but the PKC signaling mechanism is not yet known. The goal of these studies was to identify PKC isotype(s) required for control of CFTR function.
ISSN:0363-6143
1522-1563