Renal renin-angiotensin system in diabetes: Functional, immunohistochemical, and molecular biological correlations

To explore the renin-angiotensin system (RAS) in diabetes, studies were conducted in nondiabetic control rats and in moderately hyperglycemic diabetic rats. To determine the basis of intrarenal hemodynamic responsiveness to RAS inhibition, biochemical, molecular biological and immunohistochemical st...

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Bibliographic Details
Published inAmerican journal of physiology. Renal physiology Vol. 34; no. 4; p. F477
Main Authors Anderson, Sharon, Ingelfinger, Julie R, Jung, Flavia F
Format Journal Article
LanguageEnglish
Published Bethesda American Physiological Society 01.10.1993
Subjects
Biochemistry
Cellular biology
Diabetes
Hypertension
Kidneys
Rodents
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Summary:To explore the renin-angiotensin system (RAS) in diabetes, studies were conducted in nondiabetic control rats and in moderately hyperglycemic diabetic rats. To determine the basis of intrarenal hemodynamic responsiveness to RAS inhibition, biochemical, molecular biological and immunohistochemical studies were conducted to assess endogenous RAS activity.
ISSN:1931-857X
1522-1466