The Pseudomonas quinolne signal regulates rhl quorum sensing in Pseudomonas aeruginosa

The opportunistic pathogen Pseudomonas aeruginosa uses intercellular signals to control the density-dependent expression of many virulence factors. The las and rhl quorum-sensing systems function, respectively, through the autoinducers N-(3-oxododecanoyl)-L-homoserine lactone and N-butyryl-L-homoser...

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Bibliographic Details
Published inJournal of bacteriology Vol. 182; no. 10; p. 2702
Main Authors McKnight, Susan L, Iglewski, Barbara H, Pesci, Everett C
Format Journal Article
LanguageEnglish
Published Washington American Society for Microbiology 01.05.2000
Subjects
Bacteria
Bacteriology
Cells
Genes
Molecular biology
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Summary:The opportunistic pathogen Pseudomonas aeruginosa uses intercellular signals to control the density-dependent expression of many virulence factors. The las and rhl quorum-sensing systems function, respectively, through the autoinducers N-(3-oxododecanoyl)-L-homoserine lactone and N-butyryl-L-homoserine lactone (C4-HSL), which are known to positively regulate the transcription of the elastase-encoding gene, lasB.
ISSN:0021-9193
1098-5530