Histone macroH2A 1.2 is concentrated in the XY compartment of mammalian male meiotic nuclei

• Published in: Cytogenetic and genome research Vol. 89; no. 1/2; p. 118
• Main Authors: Richler, C, Dhara, S K, Wahrman, J
• Format: Journal Article
• Language: English
• Published: Basel S. Karger AG 01.01.2000

We show here that histone macroH2A1.2 concentrates at the transcriptionally silent XY body, normally being formed during male meiosis in the mouse. A similar accumulation has earlier been observed on the inactive X chromosomes of somatic adult female mammalian cells by Costanzi and Pehrson (1998). T...