ON DYNAMICAL (B/GD) NEUTRON CANCER THERAPY: ACCELERATOR-BASED SINGLE NEUTRON BEAM
This paper investigates a dynamical one-dimensional reaction-diffusion model of slow neutron beam radiotherapy for the treatment of tumors. The subject of an accelerator-based single-beam boron neutron cancer therapy (BNCT) and /or GdNCT is revisited in light of possible time modulation. The associa...
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Published in | Pacific journal of applied mathematics Vol. 9; no. 1; pp. 9 - 26 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Hauppauge
Nova Science Publishers, Inc
01.01.2017
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Subjects | |
Online Access | Get full text |
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Summary: | This paper investigates a dynamical one-dimensional reaction-diffusion model of slow neutron beam radiotherapy for the treatment of tumors. The subject of an accelerator-based single-beam boron neutron cancer therapy (BNCT) and /or GdNCT is revisited in light of possible time modulation. The associated propagation of a one-speed neutron-density wave in a cancerous region is proved to decompose into dissipative and periodic parts. The periodic part is shown to be a quasi-standing wave. It is also demonstrated how the modulation frequency of the accelerator can possibly be employed in the formulation of an optimization process that maximizes a therapeutic utility index together with the ballistic index for these-neutron density waves. |
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ISSN: | 1941-3963 |