Diagnostic value of white light bronchoscopy combined with autofluorescence bronchoscopy for early diagnosis of lung cancer: a systematic review / 普通支气管镜联合自发性荧光支气管镜在肺癌早期定位诊断中的系统评价

Objective: To evaluate the diagnostic value of white light bronchoscopy combined with autofluorescence bronchoscopy (AFB) for early diagnosis of lung cancer by meta-analysis. Methods: We searched PubMed, ISI Web of Knowledge, Chest, Cochrane and other databases (1990-2010) to collect studies which e...

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Published inXi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban no. 6; p. 733
Main Authors ZHANG, Wei, Wei-lin, YANG, YANG Shuan-ying, HUO Shu-fen, Wen-li, SHANG, DU, Jie, Xiu-li, LIN, Li-na, BU
Format Journal Article
LanguageChinese
Published Xi'an Xi'an Jiaotong University 01.01.2011
Subjects
Lung cancer
Meta-analysis
Systematic review
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Summary:Objective: To evaluate the diagnostic value of white light bronchoscopy combined with autofluorescence bronchoscopy (AFB) for early diagnosis of lung cancer by meta-analysis. Methods: We searched PubMed, ISI Web of Knowledge, Chest, Cochrane and other databases (1990-2010) to collect studies which evaluated the diagnostic value of AFB for early diagnosis of lung cancer. The heterogeneity of included studies was tested by Meta-Disc1.4 software. The diagnostic value of WLB combines AFB for early diagnosis of lung cancer was evaluated by the pooled sensitivity, specificity, the likelihood ratio (LR) and summary receiver operating characteristic curve (SROC curve) statistical indicators. Results: Ten articles were collected and 2157 cases were included in the studies. Totally 4804 biopsies were obtained and 2183 specimens were confirmed to be moderate or severe dysplasia, carcinoma in situ (CIS) and invasive cancer by pathology. Heterogeneity was found except for threshold effect. A meta-analysis was performed us
ISSN:1671-8259