Correlation between LDL-c to HDL-c cholesterol ratio and intracoronary in-stent restenosis / LDL-c/HDL-c与冠状动脉介入术后支架内再狭窄的相关性

• Published in: Xi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban no. 3; p. 323
• Main Authors: Xiao-huan, LIU, Wei-dong, MA, Yang, ZHENG, JIA Shan, Ya-jie, FAN, Zhi-hui, YAO, Chun-yan, ZHANG, ZHANG, Yan, Yan-chao, HU, GE Miao, Cong-xia, WANG
• Format: Journal Article
• Language: Chinese
• Published: Xi'an Xi'an Jiaotong University 01.01.2018
• Subjects: Statins; Stents
• ISSN: 1671-8259
• DOI: 10.7652/jdyxb201803005

Objective: To study the relationship between LDL-c/HDL-c ratio and instent restenosis (ISR) after percutaneous coronary intervention (PCI). Methods: : For this study we made a retrospective analysis of 216 patients who underwent stent implantation and received coronary angiography (CAG) from October 2009 to October 2016 in the Second Affiliated Hospital of Xi’an Jiaotong University. The subjects were divided into ISR group (73 cases) and non-ISR group (163 cases) based on CAG outcome. Then based on the general data and LDL-c/HDL-c ratio of the two groups of patients, we marked them as T1, T2 and T3 groups to explore the relationship between LDL-c/HDL-c and ISR. Results: ① Compared with that in the control group, LDL-c/HDL-c ratio was significantly higher in ISR group (P<0.01). ② ISR was higher in high LDL-c/HDL-c group than in low LDL-c/HDL-c group (P<0.05). ③ Multivariate logistic regression analysis showed that LDL-c/HDL-c ratio and diabetes mellitus were independent risk factors for ISR in patients who und