Inactivation of the integrin beta6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lungs and skin

A study suggests that the epithelial integrin alpha nu beta6 participates in the modulation of epithelial inflammation. Genetic or acquired alterations in this integrin could contribute to the development of inflammatory diseases of epithelial organs, such as the lungs and skin.

Saved in:
Bibliographic Details
Published inThe Journal of cell biology Vol. 133; no. 4; p. 921
Main Authors Huang, Xiao-Zhu, Wu, Jian Feng, Cass, Darrell, Erle, David J
Format Journal Article
LanguageEnglish
Published New York Rockefeller University Press 01.05.1996
Subjects
Cellular biology
Genes
Lungs
Mutation
Skin
Online AccessGet full text

Cover

More Information
Summary:A study suggests that the epithelial integrin alpha nu beta6 participates in the modulation of epithelial inflammation. Genetic or acquired alterations in this integrin could contribute to the development of inflammatory diseases of epithelial organs, such as the lungs and skin.
ISSN:0021-9525
1540-8140