THE THERAPEUTIC MANAGEMENT IN COLONIC DIVERTICULAR DISEASE - A REVIEW

The recurrence of diverticulitis after a first episode was estimated at 15-30%. [...]the colonic diverticular disease represents a challenge in daily medical practice, having an important impact upon the health system12. [...]German guidelines support the efficacy of Mesalazine as the only form of t...

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Published inResearch and science today p. 66
Main Authors Bobic, Simona, Socea, Bogdan, Diaconu, Camelia, Bratu, Ovidiu, Marcu, Dragoş, Manea, Maria, Berteşteanu, Şerban, Cojan, Tiberiu Stefanita Tenea, Băleanu, Vlad-Dumitru, Constantin, Vlad Denis
Format Journal Article
LanguageEnglish
Published Targu-Jiu University Constantin Brancusi of Târgu-Jiu 01.01.2018
Subjects
Abdomen
Abrasion
Antibiotics
Chemical compounds
Clinical trials
Colon
Dietary fiber
Disease
Disease control
Disease management
Disorders
Fibers
Guidelines
Irritable bowel syndrome
Management
Medical practices
Mucosa
Pain
Pathogenesis
Pathology
Patients
Pharmacology
Probiotics
Risk analysis
Risk factors
Sepsis
Smoking
Studies
Therapy
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Summary:The recurrence of diverticulitis after a first episode was estimated at 15-30%. [...]the colonic diverticular disease represents a challenge in daily medical practice, having an important impact upon the health system12. [...]German guidelines support the efficacy of Mesalazine as the only form of treatment in uncomplicated symptomatic diverticular colonic disorder, while Italian guidelines do not consider Mesalazine as a valid therapeutic option in the management of this pathology. Smoking, sedentary and poor diet in fibers are risk factors for the occurence of acute diverticulitis26. [...]10 years ago, antibiotics were considered as mandatory therapeutic agents in the management of acute diverticulitis, even in mild forms, based on the idea that diverticulitis is the consequence of obstruction of a diverticulum, secondary mucosal abrasion, microperforation and bacterial translocation27. A Cochrane review evaluated the effectiveness of antibiotic therapy in cases of uncomplicated acute diverticulitis, with results supporting recommendations from recent European and American guidelines to individualise the indication of the antibiotic therapy. [...]administering antibiotics to patients with uncomplicated acute diverticulitis may be indicated for patients with sepsis or severe infections, or those with severe concomitant disease or immunosuppression29.
ISSN:2247-4455
2285-9632