Free radical lipid oxidation in brain cortex neurons and neuroglia during convulsions

The amount of lipid peroxidation products (conjugated dienes and trienes and Schiff bases) in cortical neurons of the cerebral hemispheres decreased by 30% at the peak of convulsions observed 10-15 min after intraperitoneal injection of picrotoxin. In neuroglial cells of control animals the intensit...

Full description

Saved in:
Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 138; no. 4; p. 341
Main Authors Flerov, M A, Tolstukhina, T I, Gerasimova, I A
Format Journal Article
LanguageEnglish
Published New York Springer Nature B.V 01.10.2004
Online AccessGet full text

Cover

More Information
Summary:The amount of lipid peroxidation products (conjugated dienes and trienes and Schiff bases) in cortical neurons of the cerebral hemispheres decreased by 30% at the peak of convulsions observed 10-15 min after intraperitoneal injection of picrotoxin. In neuroglial cells of control animals the intensity of lipid peroxidation in was 1.7-2.0 times lower. Picrotoxin had no effect on this parameter.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-005-0094-8