Extranodal lymphoplasmacytoid lumphoma (immunocytoma) presenting as small intestinal obstruction: A case report and review of the literature

A 57-year-old woman presented with intermittent symptoms of intestinal obstruction. Workup provided nondiagnostic radiologic studies. An exploratory laparotomy revealed a segmental dilatation in the proximal ileum, which showed diffuse thickening of the intestinal wall. Microscopic examination of th...

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Published inArchives of pathology & laboratory medicine (1976) Vol. 125; no. 5; p. 677
Main Authors Recine, Monica A, Perez, Maria T, Cabello-inchausti, Beria, Lilenbaum, Rogerio C, Robinson, Morton J
Format Journal Article
LanguageEnglish
Published Northfield College of American Pathologists 01.05.2001
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Literature reviews
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Summary:A 57-year-old woman presented with intermittent symptoms of intestinal obstruction. Workup provided nondiagnostic radiologic studies. An exploratory laparotomy revealed a segmental dilatation in the proximal ileum, which showed diffuse thickening of the intestinal wall. Microscopic examination of the affected area disclosed a diffuse transmural infiltrate composed of small lymphocytes, mature plasma cells, and lymphoplasmacytoid cells in different stages of maturation associated with extracellular periodic acid-Schiff-positive material. In addition, serum protein electrophoresis showed a monoclonal immunoglobulin M kappa paraprotein. Postoperative workup did not demonstrate evidence of systemic involvement. The morphologic features and immunohistochemical and molecular analyses were consistent with lymphoplasmacytoid lymphoma (immunocytoma). We report an unusual case of primary extranodal immunocytoma involving the small intestine and discuss its clinicopathologic features.
ISSN:0003-9985
1543-2165