CIGARETTE SMOKING EFFECTS ON LIPID PROFILE

According to WHO (2011) tobacco is responsible for about 5 million deaths each year of which 100,000 deaths occurs in Pakistan. Four reasons have been hypothesized. 1) Increase level of carbon monoxide(Zevin et al, 2001) in blood of smokers may injure the endothelium and speed up the cholesterol lev...

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Published inFUUAST jounral of biology Vol. 8; no. 1; pp. 153 - 156
Main Authors Khwaja, Sobia, Mushtaq, Rubina, Mushtaq, Rehana, Akram, Ambreen, Rehman, Attiya Sabeen, Jamal, Qaiser
Format Journal Article
LanguageEnglish
Published Karachi Federal Urdu University of Arts, Science and Technology 01.06.2018
Subjects
Cardiovascular disease
Chronic illnesses
Cigarette smoking
Disease prevention
Health risk assessment
Low density lipoprotein
Atlanta Georgia
Pakistan
United States > US
Karachi Pakistan
India
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Summary:According to WHO (2011) tobacco is responsible for about 5 million deaths each year of which 100,000 deaths occurs in Pakistan. Four reasons have been hypothesized. 1) Increase level of carbon monoxide(Zevin et al, 2001) in blood of smokers may injure the endothelium and speed up the cholesterol level into the artery wall which is the cause of atherosclerosis (Bano et al., 2002) 2) The formation of carboxyhemoglobin creates relative anoxemia in tissue including the myocardium (Sagcan et al., 2003) 3) The nicotine absorbed from cigarette smoke induces cardiac arrhythmias through its pharmacologic action. 4) An another mechanism has been recently suggested that smoking harmfully affect the concentration of lipid in plasma and lipoprotein However, there are few international studies available about the relationship of tobacco smoking and plasma lipid levels but the results are inconclusive and conflicting. Exclusion criteria * Subjects having history of diabetes mellitus, nephrotic syndrome, alcoholism, hypertension were excluded. * Subjects on HMG COA reductase inhibitors, fibric acid derivatives, nicotinic acid, beta-blockers, diuretics. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. [accessed 2015 Oct 5]. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014 [accessed 2015 Oct 5].
ISSN:2222-0356
2616-8758